How DMSO Treats ‘Incurable’ Autoimmune and Contractile Disorders

Dimethyl sulfoxide (DMSO) is a simple and readily available naturally occurring chemical that rapidly enters the body through the skin and has a variety of remarkable therapeutic properties. When it was discovered, its proponents realized it represented a new therapeutic principle in medicine and once adopted, would completely change how medicine was practiced.

In turn, they conducted thousands of studies demonstrating DMSO’s overwhelming safety and efficacy in hundreds of thousands of people, but unfortunately, the FDA conducted a reprehensible campaign against DMSO¹ that eventually made it become a Forgotten Side of Medicine.

Over the last month, I’ve begun presenting that evidence. For example:

• I showed here how DMSO transforms the management of strokes, spinal cord injuries, mental disability and a variety of circulatory disorders (e.g., Raynaud’s, Varicose Veins and Hemorrhoids).
• I showed here how DMSO treats chronic pain, arthritis, burns, wounds and traumatic injuries (e.g., sprains and sports injuries) here.
• I showed here how DMSO is one of the safest medical substances in existence.

In turn, colleagues such as Pierre Kory have begun using DMSO and reporting remarkable results. Likewise, I’ve received hundreds of extraordinary stories from readers who’ve gotten their lives back thanks to DMSO (which can be read here) and match exactly what the early pioneers of DMSO saw. Today, I will focus on some of the other critical uses for DMSO.

Note: While I have my own preferred brands of DMSO, most formulations work. When purchasing DMSO, if getting the liquid form, it is important to make sure the DMSO is of high purity and stored in a glass container (the gel form also works and is easier to apply but is also more likely to be irritating and not always as potent).

When applying DMSO topically, it is important to make sure you are not allergic to it (with a small skin test), that your skin is clean (so no chemical toxins are accidentally absorbed as well) and to only use the maximum concentration one’s skin easily tolerates (which typically is 70% but can vary from 30% to 100%).

DMSO and Protein Disorders

DMSO offers a groundbreaking approach to treating complex illnesses by stabilizing misfolded proteins,² a key issue in many genetic disorders. Unlike pricey drugs that attempt to manage these disorders with limited success, DMSO’s protein-folding support can treat a broad range of conditions, including cystic fibrosis,³ amyloidosis^4,5,6,7 and even challenging neurological diseases.^8,9,10 DMSO’s effect here is remarkably universal.

Note: Improving the physiologic zeta potential (an approach we typically use to treat circulatory disorders) can also stabilize protein folding (while worsening it causes aggregation and misfolding). Likewise, DMSO has been shown¹¹ to dissolve numerous enzymes without irreversibly inhibiting them, which authors felt suggested DMSO could compensate for genetically defective enzymes.¹²

Remarkably, DMSO has shown promise in treating prion diseases like Creutzfeldt-Jakob,¹³ Alzheimer’s,¹⁴ and Parkinson’s. Testimonials reveal DMSO’s power, with reports of improved movement, energy, and coordination. For example, one reader using it for Parkinson’s experienced reduced stiffness, faster movement, and improved motor skills.¹⁵

While I am very open-minded to unconventional medical ideas and knew DMSO could treat a variety of otherwise incurable neurological diseases (e.g., ALS), there was one thing I always had a bit of difficulty believing.

DMSO allegedly had been shown to cure Down Syndrome, demonstrated both in three clinical trials^16,17,18 and remarkable case reports¹⁹ that were presented by multiple corroborating medical witnesses in Congressional testimony, along with numerous studies showing DMSO improved the cognition and behavior of developmentally delayed children.^20,21,22,23

To explain this impossible benefit, I theorized it was likely due to DMSO’s protein stabilizing benefits, as Down Syndrome is characterized by “the aberrant accumulation of unfolded/misfolded proteins resulting from over-burdened protein quality control systems.”²⁴

What I find particularly noteworthy about this is that the “untreatability” of genetic disorders (which typically result from a dysfunctional protein) has justified spending incredible amounts of money on both research and treatments for them (e.g., the industry is still in its early stages but 20.4 billion is already spent each year on gene therapies in the United States²⁵ — which in part explains why there was such a push to bring the unsafe mRNA platform onto the market and open up a massive new drug sector).

In contrast, DMSO is virtually free and has been shown to treat many of these disorders we still do not have a good option for.

Collagen Disorders

Abnormal collagen buildup contributes to many diseases, including rheumatologic and degenerative aging conditions. DMSO, known for addressing protein buildup, also “softens” collagen, benefiting various collagen disorders. It helps by:

• Regulating MMP-9 activity to support orderly healing, reducing fibrotic diseases.²⁶
• Reducing adhesions from surgery²⁷ and eliminating radiation-induced fibrosis.²⁸
• Treating keloids²⁹ by loosening collagen bundles³⁰ to flatten scars.
• Strengthening incisions³¹ and scars to prevent excessive scar formation³² post-surgery.

Note: Many other reports of DMSO benefitting collagen disorders (e.g., this symposium, which provided data on 9,521 patients with a variety of conditions such as Dupuytren’s contractures³³) also exist.

DMSO has shown promising effects on collagen-related disorders like Dupuytren’s and Peyronie’s, both of which involve abnormal collagen buildup. Early studies, including one from 1965,³⁴ showed that DMSO improved range of motion in scleroderma and reduced plaque in Dupuytren’s contracture.

How DMSO Treats ‘Incurable’ Autoimmune and Contractile Disorders